Substitute Pills Exercise?

Written By Bersemangat on Jumat, 01 Juli 2011 | 18.12

It sounds impossible, but that's what is being attempted and may be successfully realized the experts in the United States. Scientists there even claim that the revolutionary discoveries will not soon become a reality.

Yes, the scientists expressed a dream to create a pill that can be present or provide benefits such as exercise - even for people with a sedentary lifestyle (inactive) - getting closer to reality.

As reported in the journal Cell, researchers in the land of Uncle Sam has now found two types of pill formulations that seem to be able to present the effects of the formation of muscle, increase stamina and even burn fat.

Research they are doing today is still limited to laboratory mice. But the result was so surprising. Thanks to this magic pill provision, the rodent was reportedly able to run longer distances around 44 percent without having to do the exercises in advance. This indicates, the same effect might be applicable to humans since mice have a number of similarities with humans.

However, the emerging concept of the invention is clearly a controversial pill would cause concern for misuse in sports. To anticipate the possibility, lead researcher Professor Ronald Evans of the Howard Hughes Medical Institute and the Salk Institute in California claimed to have created a kind of test to detect substance use or the pill in the urine and blood of athletes.

Evans said the creation of a drug that actually has benefits and offers hope to help overcome muscle disease (muscle wasting) as well as help improve the benefits of exercise in those at risk or have diabetes.

Instant Endurance

Two types of pill, named GW1516 and AICAR, Evans explained, works by influencing the type of the gene responsible for the establishment and regulation of muscle. Master of this gene called PPAR-delta, he added, has the ability to control the activity of other genes. Therefore, if the master of this gene can be regulated or tuned, in theory influence will spread in the body of work.

In genetics, the researchers say, altering mice to enhance the activity of genes that stimulate the formation of muscle tend to like to burn fat than burn sugar. It will also create a mouse to "marathon runner" who can continue to survive while doing the treadmill.

The next stage is to produce the same effect using a drug instead of creating genetic changes. The first version of this pill called GW1516 is able to produce fat-burning effect, but does not cause improvement in the ability to practice / exercise until the rats menjalanui long treadmill sessions. At the end of the circuit this process, the mice given the drug capable of running mileage 77 percent farther than mice that practice without medication.

Second second pill called AICAR even a step further. This drug has a different way of treating the mechanism of muscle cells are different. This time, the mice do not need to practice. After four weeks of taking pills, they can travel a distance of 44 more while undergoing a treadmill without any prior training.

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